DECAPEPTYL

Consist of Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. It is also used as therapy in cases of gender dysphoria. Triptorelin is marketed under the brand names Decapeptyl (Ipsen)

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Description

Triptorelin is a type of hormone therapy drug called a gonadotropin releasing hormone blocker. It lowers the level of testosterone in men and oestrogen in women. It does this by stopping the release of luteinising hormone from the pituitary gland. In men, this stops the testicles producing the male sex hormone, testosterone. In women, it stops the ovaries from producing oestrogen.

Prostate cancer depends on testosterone, to grow. Hormone therapies that lower the level of testosterone can slow down the growth of cancer or shrink it.

Some breast cancers depend on oestrogen to grow. Lowering the level of oestrogen can slow or stop the growth of the cancer.

Manufacturer by:  IPSEN PHARMA BIOTECH, FRANCE

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